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For three weeks, participants were placed on 28-hour days with six hours of sleep, which gave them an average of 5.6 hours of sleep per night and mirrored the effects of chronic jet lag.
The effects of transient reduction of PSMD2 mirrored the effects of stable PSMD2 reduction.
Selective FHL isoform knockdown in NRVMs attenuated HDAC5 phosphorylation in response to stimulation with ET1 or PE, in a manner that mirrored the effects of these loss-of-function interventions on PKD phosphorylation.
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Remarkably, vasopressin administration mirrored the effect of the genetic region encompassing the vasopressin gene: It decreased nest building in both fathers and mothers, but it left other aspects of parental care unaffected.
Here we show that changes in WPE with rising temperatures mirrored the effect of increases in rainfall (Fig. 3b), suggesting that WPE may be set to continue under global warming scenarios.
Interestingly, overexpression of not4L35A mostly mirrored the effect of NOT4 overexpression except that it had a slightly less negative effect on growth in nup1Δ and nup120-1 cells and no detectable effect in nup49-313 cells (Figure 4C).
Interestingly, overexpression of NP in A549 cells mirrored the effect of IAV infection on cellular apoptosis.
In line with this observation, the functional deletion of the NES by mutating key residues mirrored the effect of LMB.
On the other hand, transversions to thymine were the most tolerated at each position save for position 3 where it mirrored the effect of C and A substitutions.
In confirmation of this, treatment of wild-type cells with Ruxolitinib mirrored the effect of IFNαβR knockout on MCP-1 mRNA induction (Fig. 3A).
However, c-FLIPS-2 siRNA-transfected cells showed increased cell death in response to WT rhTRAIL and DR5 antibody, but not to DR4 antibody; that is, c-FLIPS knockdown mirrored the effect of DN Egr-1.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com