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Type species of the Parvovirinae include minute virus of mice, human parvovirus, and Aleutian mink disease virus.
The protoparvovirus early promoters, e.g. P4 of Minute Virus of Mice (MVM), play a critical role during infection.
The human bocavirus (HBoV), a newly discovered parvovirus, is closely related to the bovine parvovirus and the canine minute virus, which are known to cause adverse pregnancy outcomes.
Activation of the minute virus of mice (MVM) P4 promoter is a key step in the life cycle of the virus and is completely dependent on host transcription factors.
During a productive infection, the prototype strain of parvovirus minute virus of mice (MVMp) induces dramatic morphological alterations to the fibroblast host cell A9, resulting in cell lysis and progeny virus release.
Among the host factors controlling HCV replication or translation in trans, several candidates are involved in mediating both of these processes, including human La protein, poly rC -binding poly rC -binding) and mice minute virus NS1-associated protein 1 (NSAP1) (Ali et al., 2000; Ito and Lai, 1997; Chang and Luo, 2006; Spangberg and Schwartz, 1999; Park et al., 2011).
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The genus Bocavirus includes the bovine parvoviruses, canine minute viruses and four species of human bocaviruses (HBoV1 -4)[8], [9].BoV1.BoV1 infection has been linked with mild to severe lower respiratory tract infections in children, frequently in association with other viral infections [8], [13], [14], [15], [16], [17], [18], [19], [20].
Alfred Crosby writes that San Francisco required its citizens to wear gauze masks -- even though the minute influenza virus could pass easily through the webbing -- and the police raided hotels to arrest the barefaced.
Parvovirus B19 (B19V) is a minute ssDNA virus associated with a wide range of diseases from childhood erythema to fetal death.
Early- and recycling-endosomes were labelled by incubating the cells with Alexa-568 labelled transferrin during the final 15 minutes of virus uptake (i.e. for 15 minutes before the cells were fixed).
After 15 or 30 minutes of virus uptake, little or no virus co-localisation with transferrin was observed (Fig. 8A F).
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