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Because the respiratory muscles are not contracting, the minute ventilation is fully controlled by the ventilator, which takes full responsibility for inflating the respiratory system.
VT with BiPAP-APRV remains within safe range when the ratio of spontaneous minute ventilation to total minute ventilation is between 30 and 40% [1].
Moreover, since PETCO2 is mainly determined by tissue CO2 production (VCO2), alveolar ventilation and CO (that is, pulmonary blood flow) [17], when stable metabolic conditions are assumed and minute ventilation is kept constant, acute changes in PETCO2 have been shown to correlate strongly with changes in CO in experimental [18 24] and clinical [25, 26] settings.
Minute ventilation is difficult to measure in field studies.
The correlation between heart rate and minute ventilation is high, the mean R2 is 0.90, suggesting that heart rate is a good predictor of minute ventilation.
The contribution of respiratory rate and tidal volume to this compensatory increase in minute ventilation is variable [ 7, 8, 9], probably because of differences in patients' ventilatory reserves.
Similar(46)
A 50% reduction in minute ventilation was obtained in healthy mechanically ventilated swine while maintaining normocarbia using the Hemolung system [ 13].
Mixed model analysis revealed that respiration rate and minute ventilation are significantly associated with workload levels and evaluator scores controlling for "vanilla baseline" condition.
In the chronic study phase, minute ventilation was lower for the fluoxetine trial (p <.05); however, there were no treatment affects on any of the other measurements.
An increase in tidal volume and a decrease in respiratory rate during respiratory response to hypoxia with short magnification of minute ventilation were predominant effects.
Although the changes in minute ventilation were small and no substantial change in PaCO2 was observed, an impairment of weight gain and a decrease in body temperature with a concomitant hypoxemia were evident during sustained chest compression.
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