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Minute ventilation did not significantly differ between PSV and NAVA with median values of 9.8 L/min (range, 8.0-10.9), and 9.6 L/min (range, 7.5-11.0) respectively (p = 0.51).
Respiratory rate and minute ventilation did not change.
Minute ventilation did not differ during application of AHME and of F&P.
Minute ventilation did not differ between PSV and BIPAP+SBmean (Table 1).
Pressure support levels (Δ pressure) and airway pressures (peak, mean and transpulmonary pressure) as well as pressure time product (PTP) and minute ventilation did not differ significantly between groups.
Similar(54)
APRV is a safe rescue mode of ventilation for hypoxemic or hypercarbic respiratory failure and requires a lower minute ventilation than does conventional modes.
However, heliox ventilation did neither allow for lower minute volume ventilation nor did it have an effect on gas exchange, lung inflammation, or lung damage in an animal model of acute lung injury.
Heart rate, oxygen consumption (VO2max), ratings of perceived exertion, respiratory exchange ratio (index of hyperventilation) and minute ventilation during maximal exercise did not differ at baseline among groups nor change with nitrite supplementation (Table 4, p>0.05, all).
In conclusion, uncontrolled oxygen administration in acute exacerbation of severe COPD has a limited effect on minute ventilation and thus does not explain the total increase in PaCO2.
Animal studies and extrapolation of clinical data suggest that ventilation does not appear to be a factor during the initial minutes of resuscitation when untreated arrest intervals are short [ 8- 11].
The only study, by Kiiski et al., investigating the effect of different TVs at constant minute ventilation in ARDS patients did not show any difference in cardiac output between low and high TV strategies [ 11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com