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There are great unmet needs, especially for those with lupus nephritis, in which good responses occur only in the minority of treated patients.
Only a minority of treated patients suffer from true infection.
Especially in hormone-refractory prostate cancer, a minority of treated patients show clinical benefit.
In fact, for many types of cancer, only a minority of treated patients will observe regression of tumor growth.
Demographic analysis of phase II and III chemotherapy trials show that only a minority of treated patients were older than 65 years [ 2, 3].
Although this is clinically significant, it is worthwhile to emphasize that only a minority of treated patients met the primary endpoint.
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Total sIL-6R levels remained elevated throughout the study in only two animals treated with ALX-0061 (R02055 and R05042) and two animals treated with TCZ (R05059 and 95031) (Fig. 7a,b), indicating exposure to active drug throughout the observation period in a minority of animals treated with ALX-0061 and TCZ.
Some documentary sources suggest that a minority of societies treated two-spirit persons disrespectfully, by kidding them or discouraging children from taking on a two-spirit role.
Active and passive Immunotherapy targeting only Aβ has been successful in many AD model animal trials; however, the more limited human data has shown much less benefit so far, with encephalitis occurring in a minority of patients treated with active immunization and vasogenic edema or amyloid-related imaging abnormalities (ARIA) being a complication in some passive immunization trials.
This national survey of 43,000 Americans found that only a minority of both treated (35percentt) and untreated alcoholics (12percentt) in the U.S. have abstained during the last year, but that the majority of the remainder have either improved or achieved full remission.
In the minority of patients treated after acute SAH in this study, it was the usual practice to withhold prophylaxis with antiplatelet treatment until the SFD was deployed; accepting a small additional risk of thrombotic complications.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com