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The visual inspection confirmed that only a minority of transcripts showed the features expected for true miRNA-driven post-transcriptional rhythmicity and that, instead, many of the non-rhythmic assignments were probably a result of noisier data (Supplementary file 1 in Du et al., 2014 and Figure 4 source data 1 for whole transcriptome gene expression plots and rhythmicity parameters).
The data reveal that while a large majority of host transcripts (∼75%) succumb strongly to SOX-mediated degradation, a sizeable minority of transcripts (∼20%) is only mildly affected by SOX.
The Ensembl set of genes is based on automatic annotation and a minority of transcripts violates the above requirements.
Polymorphisms identified in probe regions could, in a minority of transcripts, confound the interpretation of the observed inter-individual variation.
Two patients had two variants TEL- AML1ex2 and TEL- AML1ex3 (weaker), owing to alternative splicing causing the skipping of AML1 exon 2 in a minority of transcripts.
Given that nonsense mutations affect only a minority of transcripts, it is feasible to assume that most cancer- and normal-specific transcripts may be transcribed into functional proteins and may contribute significantly to the cancerous phenotype.
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While the majority of DLPD entries can be associated to a known gene, a substantial "silent" minority exists of transcripts that could not find any significant match against a variety of sequence databases.
The ANC1 transcript belongs to a minority of yeast transcripts that contain a splice site.
Ka/Ks analysis revealed that majority of the analysed F. hepatica transcripts (89.63%) have Ka/Ks < 0.5, hinting a purifiying selection against nonsynonymous changes as expected, a minority of the transcripts (3.37%) have Ka/Ks > 1, and a tiny portion of the transcripts (0.24%) have Ka/Ks = 1.
A smaller percentage of F. hepatica transcriptome showed homology with the data of Vaccine Investigation and Online Information Network (Violin), but only a minority of these transcripts (0.29%; n = 117) were not observed in the category of NVTs and these transcripts were termed VTs (E value < 10−5; Table 1b).
During data analysis, sections of a minority of interview transcripts were considered unusable as participants' responses were affirmations or reiterations of the researcher explanations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com