Sentence examples for minority of resistant from inspiring English sources
However, due to a significant minority of resistant pathogens, close liaison with Microbiology is recommended.
Underlying this is an assumed mixed infection, composed predominantly of sensitive strains but with a small minority of resistant strains.
A minority of resistant patient's samples displays reactivation of the AKT/PI3K pathway (but not the MAPK pathway), through activating mutations in AKT1/3 (Shi et al, 2012, 2014a) and PIK3CA (Shi et al, 2014b; Van Allen et al, 2014) or through loss or mutational inactivation of PTEN(Shi et al, 2014b; Van Allen et al, 2014).
It is thus possible that a minority of apparently resistant tumours may be sensitive to the action of AIs but extended treatment is required before clinical response becomes manifest.
Most studies suggest that ABC transporter expression must be at a moderately high level to solicit the differential sensitivity phenomenon; thus, it might be that only a minority of multidrug-resistant cells are susceptible to this treatment.
However, with a minority of epirubicin-resistant patients harbouring CHEK2 mutations, there is not yet any clinical rationale for recommending CHEK2 gene sequencing as a routine test in breast cancer patients.
This is the first documentation of MTCT of a minority resistant strain of HIV-1.
Our report highlights the importance of transmission of resistant minority strains, as it carries the threat of emergence of multi-drug resistance primary mutations without specific selective pressures.
Nonetheless, there is a significant minority of TGCT that are resistant or become treatment resistant, suggesting that a better understanding of the molecular biology of this cancer would be valuable with regard to determinants of chemotherapeutic efficacy (Jones and Vasey, 2003).
However, the presence of resistant minorities can lead to sequence heterogeneities that often result in unidentifiable residues.
Under the presence of antibiotics, the resistant minority of bacteria within the host take over at rate ρ as a function of the resistant strain replication rate, the reduced sensitive strain replication rate, and the death rate of sensitive bacteria from antibiotic exposure.
