Sentence examples for minority of mutations from inspiring English sources

However, the vast majority of mutations are neutral, and the minority of mutations which are beneficial or harmful are often situational; a mutation that is harmful in one environment may be helpful in another.

A minority of mutations causes the production of structurally abnormal type V collagen, the secretion of which may be impaired but not completely abolished [5], [6], [7].

In the other two subjects (6 and 25) a small minority of mutations was shared.

A minority of mutations in the BRCA1/ 2 genes are large rearrangements (LRs) of DNA segments that disrupt gene function.

As in the whole exome data a small minority of mutations was shared, with just two of 78 (2.6%) variants found to be ubiquitous among the seven cancer foci.

We cannot exclude the possibility that a minority of mutations have been missed, but under test conditions we have found that CSGE can detect all small insertions or deletions and 70% of single base substitutions.

Having a method to sift the minority of causal mutations from the majority of hitchhikers allowed us to use mutators and increase the speed of evolution.

The high frequency of clustered doublets, the exponential distribution of spacing, the occurrence of in-frame clustered OMIDI pairs, the allelic nature of doublets, and the clustering of multiplets in EGFR and TP53 are consistent with a significant minority of chronocoordinate mutations in human cancer.

We then developed a strategy to identify the small minority of genuine mutations.

A minority of these mutations were detected in treatment-naive patients.

A minority of nonsynonymous mutations may have been driven to high frequency by positive selection (which would downwardly bias our estimates), although positive selection acting on intron splice sequence mutations is also conceivable.