Sentence examples for minor variants at from inspiring English sources

Exact(5)

TaqMAMA detected consistently minor variants at a level as low as 0.1%.

The V3 loop forms associated with subsequent virologic failure, either through CXCR4 use or the emergence of high-level VVC resistance, were present as minor variants at 0.8 2.8% of baseline samples.

For example, NGS provides greater sensitivity to detect minor variants at high depth of sequencing coverage, copy number estimation and a feel for heterogeneity of a given biopsy.

This analysis clearly indicates that when the minor variant is present at a low frequency, the Illumina MiSeq systematically detects the minor variants at significantly higher frequencies than the Ion Torrent PGM.> -wrap-foot> #not present in Genbank or Influenza Research Database.

Note that the GATK SelectVariants tool provides the E9 and L5 variants with the greatest mapped-read frequency for display on Genoverse: minor variants at a particular locus are not displayed as they are assumed to be due to false mapping rather than genuine heterozygosity in these inbred lines.

Similar(55)

The remaining identified minor variants excise at least one exon encoding a Josephin domain catalytic residue (indicated by asterisks in Figure 1B), and thus are not predicted to encode functional deubiquitinating enzymes (DUBs).

A total of 164 consecutive adults with newly confirmed stage IIIB, IVA or IVB Hodgkin's disease (HD) commenced cyclical combination chemotherapy comprising mustine, vinblastine, prednisolone and procarbazine (MVPP) every 6 weeks (145 patients) or minor variants (19) at St Bartholomew's Hospital between 1968 and 1984.

However, we believe that this is not the case for two reasons: First of all, we have set the minority cutoff to 5% to mirror the one of the original trofile assay which was reported to be 100% sensitive at detecting 10% minor variants and 85% sensitive at detecting 5% minor variants in a mixed virus population.

If we require ≥ 4 reads per variant while keeping the threshold of minor variant abundance at ≥ 10%, the correct predictions rise to 75% (9/12).

Markers were considered polymorphic and retained for analysis if the minor variant occurred at a frequency of ≥2.5% across all individuals.

When considering AS according to 454 reads alone, 64% (80/125) of the well-supported cases of AS are predicted correctly, which increases to 79% (30/38) if we require ≥ 4 reads per variant while keeping the threshold of minor variant abundance at ≥ 10%.

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