Sentence examples for minor transcripts from inspiring English sources

Minor transcripts with small molecular masses were attributed to RNAP pausing sites since no obvious promoter sequences could be predicted in the putative upstream regions.

Two minor transcripts, referred to as BL42 and BL56, expressed parts of ZFR30 and of the unique region Ub and full length SAB and CTD domains.

Interestingly, a previously reported COL5A1-acceptor-splice site mutation (IVS4-2A>G) does not only affect the splicing of exon 5, but also of the downstream exon 6 [11], and also generates two minor transcripts by using a cryptic splice site in exon 5.

Expression of the two minor transcripts, c and d, was also associated with the rs4072037 allele.

From this region, two minor transcripts seemed to originate that had retained intronic sequences (Table S5 ).

For example, cases predicted to have 2 5% minor transcripts are validated with a rate of 25% whereas cases predicted to have more than 5% minor transcripts are validated with a rate of 64% (Table 2).

In both Huh7 and J328 cells, there were minor small transcripts (two and one out of the 10 clones, respectively) with the absence of exons 2 6 resulting in conjunction of exon 1 to exon 7, suggestive of transcripts derived from an alternative splicing process.

Based on gene expression studies, an authentic transcript tends to be maintained the major function, whereas a minor transcript tends to be free from selective pressure and ready to acquire a novel function31.

In our setting (~35 M reads per sample) and at this level of expression (FPKM = 0.5), we expect to find ~15 reads per sample for each kb of the minor transcript, providing high power for the detection of both isoforms.

Although successful design of an effective duplex specifically targeting the minor transcript was not achieved (Fig 4C), one of the 3 duplexes targeting the major NGLY1 transcript selectively silenced this transcript without silencing the minor transcript (NGLY1 Long-3).

HNF4A9 transcripts comprised a minor transcript in rodent islets, as in human islets [17], although levels were slightly higher in rat comprising 22% of total islet HNF4A expression compared with 9% in man and 4% in mouse; p = 0.006.