Sentence examples for minor sequence mutations from inspiring English sources
After linkage analysis, 9 of the 13 polymorphic loci of pre-miRNAs were mapped on 7 cotton chromosomes (Chr01, Chr04, Chr13, Chr15, Chr16, Chr23 and Chr26) based on SSCP analysis which can discover minor sequence mutations and reveal more polymorphisms to map genes [ 35].
All 28 binders showed different sequence mutations.
While the previous analysis of the amino acid sequences of these proteins identified critical differences at some conserved sites in the primase domain region of the protein in metazoa, including the absence of the cysteine residues needed to form the zinc fingers [ 4, 5], we wanted to know if these changes were due to minor mutations in the sequence.
Phylogenetic analysis using pyrosequencing reads containing specific minor protease mutations again showed that these reads overwhelmingly clustered with the correct number of Sanger sequences containing the concordant mutations.
Screening of HIV-1 genomic sequences from patient TV721 with the HIVdb Genotypic Resistance Interpretation Algorithm (http://hivdb6.stanford.edu/asi/deployed/HIVdb.html) showed minor resistance mutations to protease inhibitors (L10I) and integrase inhibitors (I203M).
The defects may be the result of several minor genetic mutations rather than the single mutation that produces seizures in the rare, highly heritable forms of epilepsy.
The impact of other minor KRAS mutations remains unknown.
The RASKET KIT detected 143 (46.6%, 143/307) mutations: 114 KRAS exon 2 and 29 minor RAS mutations.
Analysis at the single cell level allowed further genetic dissection, as conventional sequencing techniques fail to detect minor mutations (Ellison et al, 2010).
The second selection process would allow minor mutations to occur in the DNA coding sequence, leading to amino acid selection and functional maintenance of the proteins under fluctuating environmental conditions.
