We first performed pairwise comparisons between the best-fit model (residual ancestral migration and nearly full replacement, δ≥0.99) and the minor replacement (δ≤0.5) models (Figure 3A).
We chose an irradiation protocol for bone marrow transplantation, which resulted in minor replacement of microglia by blood-borne cells prior to cerebral ischaemia, and negligible contribution of donor-derived cells to the resident microglial pool was observed within 24 hours reperfusion after cerebral ischaemia.
For example, The N-[VI] motif asparagine within Arf/Arl GTPases could be mutated to an aspartate (a relatively minor replacement of the side-chain -NH2 group with an oxygen atom) to explore the influence of the -NH2 group on the interswitch toggle device and, as a result, perhaps on GEF or GAP activity.
While small upgrades and minor decor replacements may seem like a waste of time when you're in a hurry to sell your house, one of the biggest mistakes you can make as a seller is listing your home without any advance preparation.
In Baseball Reference's Offensive Wins Above Replacement (measuring offensive contributions above a typical minor league replacement), Allen was the best hitter in his league three times and in the top five eight times in a nine-year span.
The study warned that lead levels appeared highest at homes where lead lines were disturbed, through street-heavy excavation or even relatively minor meter replacement.
In the Swedish register, the reoperations are subdivided into 3 groups: (1) revision with replacement or extraction of implant components, (2) major reoperations without replacement or removal, and (3) minor reoperations without replacement or removal.
At the protein level, these genomic rearrangements account only for minor amino acid replacements relative to the expected KLK3 sequence (S231P, R239K, S241A, L242V, and V258A).
Often the joke is meant to be Jupp's impotent rage at life's minor inconveniences: the replacement of buttons by touchscreens; being mistaken for a trainspotter.
The irradiation dose was selected to enable effective repopulation of haematopoietic cells (Bigger et al., 2006), but resulted in only minor (1 4%) replacement of hemispheric microglia by donor-derived cells after 6 8 weeks.
