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Saxonov et al (2006) discovered a bipartite distribution of gene promoters with minor overlap between both classes when categorising promoter sequences by means of their CpG content.
Other studies show only a minor overlap between ATRX mutation and K27M (Fontebasso et al. 2014; Wu et al. 2014) or no mutations in ATRX in K27M tumors (Taylor et al. 2014a).
A comparison of the transcriptional profile of roots grown in soil (this work) with that of roots grown hydroponically [ 28] showed only a minor overlap between these two growth systems.
The difference in LOD peak location and only minor overlap between these two QTL may also indicate that these are separate, linked loci of opposite effects that are most pronounced in contrasting environments.
We detected only minor overlap between neurons that stained positive for ChAT and those that expressed GFP in the NB, GP, MS/DBB, or PPN, except for cortical ChAT+ interneurons, where we observed significant overlap (GFP+/ChAT + neurons: Ctx: 122/136; MS/DBB, 1/573; NB, 0/439; GP, 7/413; PPN, 12/246, Figure 3 figure supplement 1).
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We anticipated only minor overlaps between the data from their paper and our results since histopathological data from our investigated bladder biopsies indicated that urothelial cells contribute only a minor part of all cell types.
The minor overlap observed between the SNP and PA sets discovered using different RE pairs apparently results from both the differences in the distribution of restriction sites and the low coverage achieved for complexity reduced libraries.
Surprisingly minor overlap was observed between the Wy14643-regulated genes from mouse and human, although more substantial overlap was observed at the pathway level.
There was nevertheless only minor overlap of targets between ICM, TE and ES cells (Figure 5D), indicating that these cell types are largely epigenetically distinct.
Mapping all genes with 5'-TOP elements of a recent study in the human genome to our list of LTSM-positive genes resulted in a minor overlap of 52 between the 1399 LTSM-positive and the 1114 TOP-positive genes including 17 RP genes [ 16].
While the number of genes commonly regulated by PPARα in mouse and human hepatocytes may seem relatively small, which would suggest minor overlap in PPARα function between the two species, the overlap is more impressive when studied at the level of gene ontology.
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