Sentence examples for minor effect variants from inspiring English sources

Minor effect variants, for example, are unlikely to be identified in linkage studies due to a combination of broadly spaced markers and limited sample sizes.

This is consistent with the idea that transcripts may be valuable when sensitivity or resistance has a complex genetic basis with many minor-effect variants rather than one major-effect variant.

The power among pre-menopausal women was of 0.81 to detect an OR of 1.3 in a log additive model, hence we cannot exclude a minor effect of the variant allele on BC risk in pre-menopausal subjects.

On the other hand, profiles found to NRs assent to the continuous high diverse population and a lower diversity between pre and post-therapy variants probably due to a minor effect of treatment in variants selection.

Altogether, our results suggest very minor effect, if any, of ATM genetic variants on familial breast cancer in Southern Finland.

Secondly, major sample sizes were acquired by international collaboration (>13 000 individuals in the study of Lambert et al. and >16 000 individuals in the study of Harold et al)., surpassing the power hurdle to detect variants with a minor effect.

Based on estimates from population-based Inter99 of 5722 nondiabetic individuals, it is evident that the common variants depicted in Fig.  1 and Table  1 individually only have a minor effect on the examined trait.

Our data suggested that the genetic variants of BMP4 may not play a dominant role in glucose metabolism in Chinese Han population, but a minor effect cannot be ignored.

Other analyzed substances had only minor effect.

Moreover even this minor effect was transient.

The selected ADH and ALDH gene variants had only minor effects, and did not seem to markedly modify the health effects of alcohol drinking.