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This suggests that cumulative and multi-focal stresses might play an important role in disease progression, by switching from local (and probably recoverable) minor dysfunctions to extended neuronal alterations like permanent synaptic, axonal or even cell bodies loss.
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On their own, these genetic variations do not cause much harm, but several together can create havoc, each representing a minor dysfunction that adds to the risk for an individual to develop a disease.
This would predict that a minor dysfunction of the hand would diminish the P200 obtained from the face.
The prognosis for minor dysfunction remains good and survivors recover from AKI, whereas renal failure still carries a high mortality.
No severe bladder dysfunction was found, although minor urinary dysfunctions, such as stress and urge incontinence, occurred in one individual (Subject 2792, Family TK005).
Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW).
To investigate the 6-month neurodevelopmental outcomes of prematurely born neonates and find the determining neonatal factors of minor neurological dysfunctions (MNDs).
Although the mean number of minor neurological dysfunctions decreased with age, there were no significant changes in the prevalence of MND.
In preterm children the development of psychopathology seems to be mediated by minor neurological dysfunctions (MND), decreased verbal abilities and family adversity.
Both ISS and SGA have been associated with problems in behavior, social functioning, school competence, and attention [ 21- 23], while SGA has also been associated with lowered intelligence and minor neurologic dysfunctions [ 21, 22, 24].
These check-ups will include a complete clinical examination and psychological tests and will evaluate, using standardized tools: – Growth, assessed by standardized anthropometric measurements; – Motor disorders, especially cerebral palsy and minor neuromotor dysfunctions.
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