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In addition, mice engineered to carry deletions in any single one of these multiple receptors exhibited no defective clearance or minor defects in embryonic development.
But these are minor defects in a book that recreates the mirror Caravaggio held up to nature with singular delicacy as well as passion and panache.
They focused on the gene for actin, a protein that links contracting muscle cells, because studies in mice and flies have indicated that minor defects in actin genes can disable a muscle.
In contrast, knockout of NEDD9 results in viable, fertile animals, with minor defects in immune system maturation [39].
Finally, this displacement leads to occasional fusion of neighbouring ommatidia and other minor defects in the pupal retina.
As predicted based upon the maternal contribution of ELMO mRNA and protein, embryos homozygous mutant for elmo19F3exhibited minor defects in axonal patterning.
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The ΔACSIα strain displayed only a minor defect in growth on either maltose or peptides, while no growth defect on these substrates was observed with the ΔACSIIα strain.
The proportion of insulin resistance versus beta cell dysfunction differs among individuals, with some having primarily insulin resistance and only a minor defect in insulin secretion and others with slight insulin resistance and primarily a lack of insulin secretion.
In addition, this indicates that the observed minor defect in complementation of sso2-1 sso1Δ cell temperature-sensitivity is not due to reduced expression levels.
Thus, although we could conclude that virions from CEM.NKR cells were able to enter the target cell, a minor defect in viral entry could not be completely excluded.
Intriguingly, although loss of Giα proteins exhibited a minor defect in Akt activation, the S6 phosphorylation was clearly impaired in Gi1/3-deficient MEFs.
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