In addition we also searched minor databases such as Eldis, WHOLIS, World Bank, USAID, Management Sciences for Health (MSH), DFID and Centre for Reviews and Dissemination (CRD) database hosted at York University, and Google scholar.
To facilitate easy interpretation for clinical purposes, a minor H database named dbMinor (http://www.lumc.nl/dbminor) was developed.
Although most of the differences are minor, no databases have identical number of interaction records compared with each other and to the number described by the authors of the original publication.
The minor H antigen database (dbMinor) supports 4 applications, i.e. the minor H antigen database (I), the minor H antigen search based upon HLA typing (II), a full donor/recipient minor H antigen and HLA typing analysis (III), and a data submission section (IV).
The minor H antigen database allows data searches for basic information on individual minor H antigens.
Moreover, a minor H antigen database has been developed providing immediate information of the potential clinical relevance of the minor H antigen typing results for the relevant donor/recipient pair.
The same data sources were available in MB as in NL, with minor differences in database characteristics.
Inexpensive methods were chosen to identify and recruit GPs; these relied on an existing database, minor promotion and a letter of invitation.
We chose inexpensive methods to identify and recruit GPs, relying on an existing database, minor promotion and a letter of invitation, and succeeded in recruiting a substantial sample of GPs.
Another sequence change at this position, p.Arg418Cys, which might be predicted to be pathogenic owing to its position within the helix termination motif, is listed on the dbSNP database (minor allele frequency from 1000 Genomes project = 1·9%) and also on the Exome Variant Server (http://evs.gs.washington.edu/EVS/), indicating that it may be a nonpathogenic sequence change.
