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To maximize the potential for successful possible future revision, several prostheses that require only minor bone loss for implantation have been developed (Morrey 1989, Walker et al. 2005, Röhrl et al. 2006).
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The bone loss occurs at a minor intensity in the shaft and reaches 35% in the femur and 25% in the tibia within the first 5 to 7 years after injury [ 3].
However, as the patients psychological profile did not permit this first surgical option, we were forced in trying a minor procedure consisting of a new radical debridement of the septic site, treatment of the bone loss with antibiotic-loaded bone substitutes (Herafill® beads G, Heraeus Medical Wehrheim) and coverage of the skin with a new muscle flap [ 7, 8].
Soininvaara et al. suggested that this less pronounced bone loss represented both operation-related and postoperative immobilization-induced bone loss, because age-related bone loss is minor [ 5].
I'm very concerned with bone loss.
BONE LOSS -- The rapid acceleration of bone loss at menopause is most effectively countered by estrogen.
Maximum bone development ends in one's 20's, after which bone loss gradually begins to exceed bone formation.
Bone loss accelerates rapidly in women after menopause.
Estrogen can also increase bone density in women who have suffered some bone loss.
But while vertebral fractures are a telltale sign of bone loss among women over age 50 and men over age 60, most who suffer them are unaware of the problem and receive no treatment to prevent future fractures in vertebrae, hips or wrists, the bones most likely to break under minor stress when weakened.
Bisphosphonates work by inhibiting cells from breaking down old or damaged bone, a beneficial effect that inhibits bone loss.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com