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The key role of SERCA in reloading the SR, and thereby indirectly modulating hiPSC-CMs whole-cell [Ca2+]i transients, was further demonstrated by the miniscule effect of caffeine in hiPSC-CMs pretreated with thapsigargin, as a result of a pronounced diminution in SR Ca2+ content.
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In fact, such reforms would have a miniscule effect on GDP, simply because agriculture is a very small part of output.
If a Zynga game is delayed, and Zynga's stock price drops, that decline has a miniscule effect on a diversified shareholder's portfolio returns.
I keep my alarm clock just outside my bedroom, which allows me to wake up early with the miniscule side-effect of being almost totally overwhelmed by agitation and puffy-eyed rage for the first two hours of each day.
The constructive effect of such miniscule, seemingly unimportant but enduring policies tend to be neglected as compared with sudden and macroevents.
The effect of obesity is therefore miniscule, reflecting less than two minutes.
While that is a miniscule amount of time, this latency has the effect of nipping predatory trading activity in the bud.
As requested, we now include current clamp data at 1, 30, and 70 μM Ca2+, showing that the effect of 1 μM Ca2+ is miniscule, whereas 30 μM evokes a sizeable hyperpolarization that saturates at ≤ 70 μM.
These emergency contraceptives would be among the safest drugs sold over the counter, [and] the number of eleven-year-olds using these drugs is likely to be miniscule.… Instead, the invocation of the adverse effect of Plan B on eleven-year-olds is an excuse to deprive the overwhelming majority of women of their right to obtain contraceptives without unjustified and burdensome restrictions".
If existing data is not convincing because the effect of tax cuts is seemingly so miniscule, proving the converse is clearly possible.
Self-tanners are a safe option for getting the effect of a tan during pregnancy, as research indicates that only a miniscule amount of the active self-tanner ingredients pass into your system during use.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com