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Proteomics, a global strategy for mining the protein information, is of great importance for developmental studies.
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We downloaded and mined the protein-protein association data from the STRING database [ 4] involving proteins from P. falciparum.
PDB Goodies is another example of resource-specific server that offers various tools for retrieving and mining the data in Protein Data Bank ([ 11], http://dicsoft2.physics.iisc.ernet.in/pdbgoodies/inputpage.html.html
With an aim to understand its propensity and energetics in ligand-protein assembly, we mined the "Pfizer protein-ligand X-ray structure database" with three-dimensional constraints for the presence of such interactions.
Hence, for a newly determined protein structure, mining the structural databases enables the identification of protein structures/sub-structures similar to the given structure [13] [18].
iHOP generates a network of genes and proteins by mining the abstracts from PubMed.
Gene Ontology (GO) [ 80] annotations for the B. azoricus sequences were provided by GOAnno [ 81] after analysis of the GO terms mined from the protein family.
In this study, to mine the protein tyrosine phosphatases (PTPs) involved in adipogenesis of human MSCs, differential expression of human PTPs was examined using RT-PCR analysis.
These two data sets were used to mine the protein sets of each sequenced Lachnospiraceae genome using USEARCH 4.0.38 (Edgar 2010) with an e-value cut off of 10− and a minimum identity cut off of 70%.
We additionally investigated the biological processes and molecular functions of these proteins by data mining the existing literature.
We found that the literature mining and the protein:protein database (PPI) toolbox embedded within the MeV package proved largely ineffective for establishing a seed network.
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