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Mining of the database revealed novel insights into the molecular mechanisms of tumor-immune cell interaction.
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Psi-BLAST mining of the databases revealed that ORFs encoding PBCV-1 Vp260 homologues are present in iridovirus genomes of CIV216R and MIV091L, but are absent in those of the ascoviruses.
Potential functional SNPs within each gene were identified through an extensive mining of the databases of the International HapMap Project and dbSNP.
Through an extensive mining of the databases of the International HapMap Project (HapMap Data Rel 24/phaseII Nov08) and dbSNP, we identified 16 potential functional polymorphisms, which were located within the 5′-UTR, 3′-UTR, promoter, coding sequence, and splice sites of nine crucial genes involved in oxidative stress response.
Once the SAGE library of interest is selected, such as GSM673.lib (indicated by the black background on the left side of Figure 1C), the detailed information for this SAGE library is provided (the right side of Figure 1C) via mining of the local database retrieved from GEO of NCBI (GSM673 is renamed GSM383828 by GEO; http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi acc=GSM383828).nih.gov/geo/query/acc.cgi acc=GSM383828
The initial data filtering and text mining of the String database were performed with the Perl programming language.
Bioinformatic mining of the growing database of bacterial genomes indicates that a large spectrum of biological and biochemical activities of RTX proteins still remains to be characterized.
In particular, we performed literature mining of the PUBMED database and constructed the herbal monomer-module gene regulatory network using the Cytoscape software.
As reference of known disease genes, a list of 93 mouse genes and gene products related to hepatic T2DM processes was generated using text mining of the PubMed database (see Methods).
Our findings from our mining of the microbiology database at Stanford University over a 20-year period indicate that (1) on a percent basis over time, the incidence of sinus-associated MRSA is rising; (2) there is no evidence of new antibiotic resistance patterns for intranasal MRSA in patients served in tertiary care institutions available in the literature.
Data mining of the COSMIC and TCGA databases did not uncover the intronic deletion in gliomas and other tumor types (not shown).
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