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eVOC, a controlled vocabulary for unifying gene expression data, is a purposely developed anatomical ontology that can integrate text mining of biomedical literature and data mining of available human gene expression data [ 39].
In order to determine the number and complete sequence of TaMET1 genes, we chose a genomic strategy based on a combination of sequence capture and in silico mining of available wheat genome sequences.
With the increasing utilization of array CGH, it has not only become important to establish standards for data deposition, but to develop tools to facilitate public access and to ease mining of available data.
At the time of submission, database mining of available cancer cell lines in the COSMIC database (http://cancer.sanger.ac.uk/cosmic/) failed to identify any other line with the p.R215W mutation, and also did not reveal any other breast cancer cell line with a coding NBN mutation, so that HCC1395 may provide a unique source for studying the molecular consequences of NBN deficiency.
Mining of available transcriptomic and proteomic data pertaining to established rodent models of epilepsy and human epileptic patients showed overrepresentation of epilepsy associated genes in our PTZ regulated set.
Mining of available ChIP data sets revealed no changes in the levels of trimethylated lysine 27 or lysine 4 of histone 3 (H3K27me3 and H3K4me3, respectively) at the PER2 promoter upon decidualization (data not shown).
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The inherent capability of PCM to combine bioactivity data for related targets, even for targets spanning distant phyla, is likely to improve the mining of currently available multi-target bioactivity databases.
The tool allows the mining of all available human EST data in a search for candidate genes with tissue restricted expression.
Our goal is to identify P. infestans genes expressed in planta through mining of publicly available ESTs corresponding to Solanaceae challenged with P. infestans cDNA libraries in compatible and incompatible interactions.
In the context of different studies, we have systematically generated MMPs through the mining of publicly available compound activity data.
Promiscuity analysis can be extended from drugs to bioactive compounds through computational mining of currently available activity data.
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