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The bail-out response explains why in Drosophila the growth of internal organs becomes independent of nutrition when larvae are starved above the minimum viable weight: because starvation sets in motion the events that lead to pupariation, and those are nutrition-independent.
However, only larvae that reach the "minimum viable weight" [ 49- 520]20] survive to adult, since the major selective factor in this occasion is the increased larval crowding.
The question of whether or not the nutrition-sensitive critical weight and the minimum viable weight are identical concepts needs to be investigated in the future.
The first one is primarily nutrition-sensitive and mediated by insulin/TOR signaling, and is triggered at the minimum viable weight (MVW), which starts a delay timer (whose mechanism is still unknown) that leads to ecdysone secretion [ 14].
Currently, there is a debate about whether the critical weight in Drosophila (the nutrition-sensitive critical weight) is the same as the minimum viable weight, which is defined as the weight that the larva must reach in order to pupariate [ 2, 10, 27].
When the two effects occur simultaneously, it is possible that selection for reducing cell area produce a genetic reduction of the "minimum viable weight", opposite to the physiological increase due to the effect of temperature, which allows a higher survival of starved larvae.
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The minimal viable size in Drosophila is also commonly called the critical weight [41], [42], [43], but, although the response of wing growth to starvation appears to be superficially similar to that we describe here for Manduca, the minimum viable size of Drosophila and the critical weight of Manduca are quite different developmental-physiological phenomena.
We need to talk about the minimum viable product (MVP).
Can you get an M.V.P. functional?' " (M.V.P. stands for "minimum viable product").
1) Build the minimum viable product to get version 1.0 shipped.
Do a quick prototype, make sure it's ugly and a minimum viable product.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com