Many states mandate a minimum trial period, usually 30 days.
Minimum trial duration was 12 weeks.
Promescent comes in two sizes: trial size and standard size.
Check out the travel and trial sizes.
Only prospective or retrospective, controlled trials with a minimum sample size of 20 patients were eligible for inclusion.
Therefore, the required minimum sample size in the present trial was N = 142 × 1.45 = 206.
The minimum sample size for this clinical trial was based on results obtained in previous studies.
Assuming a conservative treatment effect of 12 points, an overall minimum sample size for a full trial of the PRP intervention would be 90 patients (45 in each group), for assumed normality of the outcome measure, using a two-armed parallel group trial based on 80% power and 5% significance.
These data emphasise the importance of including controls in any study of cartilage damage progression in RA and provide some indication of minimum group size for future clinical trials.
After considering the outcomes of interest for this review, a minimum sample size of 50 randomized patients per trial arm was chosen, in order to be as inclusive as possible while still minimizing inclusion of randomized phase II trials.
