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To overcome these limitations, advanced drug delivery systems (DDS) aim at maximum therapeutics efficiency, enhanced bioavailability, targeted drug release, extended drug release profile, minimum toxicity, and reduced dosage frequency to encourage patient compliance.
All patients completed their CRT as planned with minimum toxicity and only one grade 3 skin toxicity.
Analyzing its antidiabetic and antilipidemic potentials could generate baseline data for development of a new therapy with minimum toxicity and high efficacy.
In addition, the biodegradable and biocompatible nature of lipids demonstrates the minimum toxicity and thus they are used for various routes of administration.
These collective findings suggest that BI 2536 might be a better and more effective therapeutic agent, in addition to its minimum toxicity and promising selectivity throughout clinical development.
Obatoclax has been used in a phase 1 clinical trial on advanced leukemic patients where it showed minimum toxicity and one patient had complete remission for 8 months [ 44].
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Furthermore, DC and DP demonstrated minimum toxicity towards vital organs and reduced gastrointestinal injury compared to DMEP and VP-16.
In order to apply the appropriate therapy, with maximum efficiency and minimum toxicity, the cancer should be diagnosed and classified correctly [ 10].
2. Retool our faltering automobile manufacturing giants, and many of our military suppliers to build super efficient cars, trains, buses, wind turbines, geothermal power plants, etc. 3. Rebuild our factories and industrial systems for maximum efficiency and minimum toxicity.
Among various cyclodextrins, HP- β-CD and SBE- β-CDs due to their high aqueous solubility and minimum toxicity are widely used in parenteral delivery.
Furthermore, bioimaging studies against L-929 cells (mouse fibroblast cells) and BHK-21 (hamster kidney fibroblast), through confocal fluorescence microscopic experiment indicated that ligand showed good permeability and minimum toxicity against the tested cell lines.
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