Sentence examples for minimum therapeutic concentration from inspiring English sources

If the patch is used, the time to minimum therapeutic concentration is 21 hours.

For most drugs, this range is wide enough, and the maximum plasma concentration of the drug (Cmax) and the area under the plasma concentration time curve (AUC) achieved when the recommended doses of a drug are prescribed lie sufficiently above the minimum therapeutic concentration and sufficiently below the toxic concentration [ 2, 3].

Hence, the length of time in which minimum therapeutic concentrations can be achieved with DOX-h-PO varies from 12 to 24 h, and for DOX-h-LA this interval is extended to at least 7 days.

Values of MIC that can be adopted in this trial can be set from 0.25 to 1.0 μg/mL [ 6, 22] Hence, the length of time in which minimum therapeutic concentrations can be achieved with Dox-pol varies from 12 to 24 h.

Typically, colonic absorption of a drug is mandatory for a sustained release formulation to hold the drug's plasma level for more than 12 or 24 h above the minimum therapeutic plasma concentration (efficacy).

A serum concentration of 0.5 μg/ml has been taken as a minimum inhibitory therapeutic concentration of oxytetracycline for most susceptible pathogens [ 9, 12].

By integrating these considerations, our model also predicts minimum therapeutic combination concentrations to maximally reduce receptor phosphorylation.

The minimum is below the therapeutic concentration range's minimum of 100 nM, while our maximum is slightly below the maximum therapeutic concentration 10 μM [ 29].

Typically, a continuous absorption of the drug for 10 20 h is necessary to maintain plasma concentration of a drug to exceed the minimum therapeutic level.

Maintaining a therapeutic concentration in the target tissue would require a series of expensive, invasive injections.

Male Cmax or AUC > (therapeutic concentration or AUC) × 500  .