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As Messina was supplied a minimum specificity requirement of 90% when these data were analysed, and this probeset could not satisfy this condition, it was rejected by Messina.
Preliminary QC and minimum specificity thresholds for CNV calls are described in greater detail in Additional file 1: Supplementary Methods.
A smaller sample size will be required for a similar precision with a minimum specificity of 75% (n = 52).
This sensitivity is consistent with the differences between the asthma prevalence recorded in this study and that recorded in published reports, and this specificity was the minimum specificity that resulted in no negative cell frequency in the corrected table.
Labeled samples were assessed by Nanodrop for sufficient quantity and a minimum specificity of 8, where specificity is the concentration of the dye (pmol/μg) times 1000 divided by the concentration of the cRNA (ng/μL).
In fact, when utilising previous diagnoses (plus anti-asthma medication usage), sensitivity increased to ≥0.8 (≥0.9 when including anti-asthma medication usage variables) at a minimum specificity of 0.9.
Similar(54)
The minimum sensitivity, specificity, precision and accuracy of the proposed fuzzy classifier system with feature extraction were 95%, 85 %, 84 and 92%and92%ectively.
Similarly, for a given region of interest and a minimum desired specificity, the necessary enrichment factor capabilities can be calculated.
When applied to ConoServer and UniProtKB/Swiss-Prot databases, ConoSorter is able to recognize 100% of known conotoxin superfamilies and classes with a minimum species specificity of 99%.
The possibility for cross-reactivity may seem high and even potentially dangerous, but given the number of potential T cell epitopes represented by modifying the 20 amino acids at each of the TCR-facing positions, it turns out that this reflects a minimum cross-specificity of 1 100,000 peptides.
Messina accepts from the user the minimum sensitivity and specificity values that all classifiers (equivalently, genes) identified must satisfy, and therefore allows the experimenter to flexibly reduce the stringency of the gene selection process.
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