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The remaining sequences were clustered using UCLUST, based on a minimum seed similarity of 99.5%.
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We also constructed a fourth model in which we assumed a minimum seed lifetime consistent with the seed viability data.
Minimum Seed Read Length was chosen to get two coverages between 12 and 25×.
For catalytic subunits, the multi seed similarity search performed allowed us to identify 1055 PI3K homologs.
SD50 was defined as minimum seeded amount causing 50% of RT-QuIC reactions to be positive.
This approach is based on the idea that looking for similar regions consists of grouping sequences that share some minimum sequence similarity over a specified minimum length.
They reported minimum interjudge similarity of 0.69, maximum similarity 0.89, and the mean of 0.76.
To obtain a similarity score it is sufficient to compare fingerprint bitsets, and the time to complete a similarity search depends mainly on the required minimum Tanimoto similarity.
Figure 11 CDF of the Minimum Jaccard Similarity Index of network states during oscillations.
Also, there was no option for setting minimum percent similarity allowed.
Two distinct sets of homologous clusters were produced based on minimum 30%and50%0% similarity.
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