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5 11 We sought to characterise the minimum prevalence and prognostic impact of each PHT subtype in a selected population using a retrospective analysis of individuals with an elevated estimated pulmonary artery systolic pressure (ePASP) on echocardiography.
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Omitting the maximum and minimum prevalence values did not change the mean markedly (IHC2+/IHC3+ combined or not specified = 32.6% vs an actual rate of 33.7%; IHC3+ only = 19.4% vs an actual rate of 20.4%).
While PDDs were previously only diagnosed in children with mental retardation, recent studies suggest that approximately 50% of individuals diagnosed with PDDs have normal intelligence [ 2], and a minimum prevalence of 2 out of every 1.000 for PDDs in mainstream school children was reported in a recent study [ 3].
Polymorphisms were selected in function of affecting the phenotype and having a minimum prevalence of 5%.
For each of the index-diseases, the most frequently co-occurring diseases were assessed, and those with a minimum prevalence rate of 10% were presented.
Thus our prevalence of 6.6% should be considered as a minimum prevalence estimate for glaucoma in small eyes, and is likely to include those at highest risk for visual impairment over their lifetime.
LHON is a common cause of inherited visual failure, with a minimum prevalence of 1 in 30 000 in Northern Europe, and with an estimated mutation carrier rate of ∼1 in 350 (Man et al., 2003; Spruijt et al., 2006; Elliott et al., 2008).
The estimated minimum prevalence of all forms of PHT in this community was 326 cases/100 000 population and for PAH specifically (group 1) the minimum prevalence was 15/100 000 population.
The probability of observing zero positives in a sample of 261 frogs is 2×10−6, using the expected minimum prevalence of 5%.
These figures are probably underestimates (i.e., minimum prevalence rates).
This enabled detection of a minimum prevalence of 20-28% depending on herd size.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com