Exact(1)
Matsubara et al. [ 4] researched for an alternative of sialic acid in order to inhibit the internalization of H1N1 and H3N2 influenza virus into host cells and their efforts were rewarded with a minimum peptide sequence ARLPR showing a good inhibitory activity (IC50 = 1.9 μM for H1N1 and 1.6 μM for H3N2).
Similar(59)
The peptide sequence was loaded into the Blast2GO program, and BLASTP with a minimum E-value of < 10-5 was performed by the program prior to mapping and annotation into GO terms.
They reported the short peptide sequence Gly-Arg-Gly-Asp-Ser (GRGDS) found in the extracellular matrix protein fibronectin to be a minimum cell adhesion ligand for integrin receptors on cell surfaces.
The antimicrobial peptide sequence used for immobilization in this research was based on a peptide previously synthesized by Hilpert et al., the Tet-124 sequence KLWWMIRRW, which shows a minimum inhibitory concentration (MIC) of 8 μg/ml against Pseudomonas aeruginosa strain H1001.
Polyacrylamide hydrogel films cross-linked with the peptide sequence AAPVAAK were synthesised on piezoelectric quartz crystals.
All peptides contain DOTA-PEG4 on the N-terminus Peptide conjugates Peptide sequence R t/min MW/u.m.a.
Tat peptide (sequence YGRKKRRQRRR) and RGD peptide (Arg-Gly-Asp) were purchased from ChinaPeptides.
A study of the peptide sequence prediction based on the steered molecular dynamics (SMD) method is presented.
These results indicated that the peptide sequence containing the four hydrophobic side chains occupying pockets within the BH3-recognition cleft of anti-apoptotic Bcl-2 proteins might be the minimum sequence required for the bioactivity and the active core region of Bim.
Related peptide sequence, CDS sequence and functional annotation are described in supplementary file S3.
This acceptor sequence was further optimized to a 15-AA acceptor peptide sequence (GLNDIFEAQKIEWHE) [236].
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