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For simulations with the minimum pedigree (D = 3, P = 0.0811, Nf = 64), the CI for R is [0.10, 0.84] when a uniform prior is assumed and [0.060, 0.70] with a uniform prior on the logarithmic scale.
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We excluded restrictive dermopathy when considering the minimum pedigree, because the only reported patient in S-leut was not included in the minimum pedigree (although the parents were included and confirmed to be carriers by genotyping) (Chong et al. 2012; Loucks et al. 2012).
In the event of multiple identical minima, the D min closest to D ori is defined as the location of the minimum.
There were no other linked pedigrees (TLOD >0.588) in the region.
"People have separated Dems from the minimum wage," Rep. Keith Ellison (D-Minn).
"They were ding-donging at each other, and I was just praying that pedigree of Unbridled would kick in," he said, referring to Unshaded's sire.
The allelic r2 for FImpute in scenario D (no pedigree information) was 0.952 for 3 k to 50 k and 0.989 for 6 k to 50 k.
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