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Furthermore, measurements of paw thickness showed similar results within groups), again the Control and Tc groups displayed minimum paw thickness.
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Both arthritic index and paw thickness were markedly improved in CIA + quetiapine treatment group compared with those in CIA groups (arthritic index; P < 0.01, paw thickness; P < 0.05).
Additional file 1: Diagram representing the effects of the total ethanolic extract and different fractions of A. hirtum leaves on paw thickness using carrageenan – induced paw edema.
Arthritic index and paw thickness were used to compare severity of arthritis.
Paw thickness was measured as above.
but did not alter the paw thickness).
Paw swelling was measured by using a dial thickness gage (Mitutoyo, Kanagawa, Japan) and was calculated as right paw thickness minus left paw thickness.
The paw thickness of each animal was expressed as the mean value of all four paws.
Additionally, increased paw thickness was considered as formation of edema.
Arthritis score and paw thickness were recorded twice weekly.
Measurements of paw thickness and paw circumference were consistent with clinical scores (data not shown).
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