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A compromise for the PIII treatment temperature must be found as the minimum particle release rate does not correspond to the minimum Co ion release rate.
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In vitro release of three formulations with maximum drug entrapment efficiency and minimum particle size, were also investigated by release kinetics.
By assuming scatter-free propagation at zero degree pitch-angle, we fitted the minimum particle path lengths (from 1.2 to 1.4 AU, as expected), and estimated the ion event release time back at the Sun to within better than 30 minutes in most cases.
If such a minimum particle were to be divided, then it would become a minimum of another substance.
Minimum particle diameter (m).
A minimum particle size of 250.8 ± 12.6 nm was achieved.
A particle fraction was operationally defined as 3 µm being the minimum particle size [36], [37].
Particle release was observed directly after impaction.
There was no detectable particle release during loading.
Particle release from the titanium particle grafts was analyzed during impaction and loading.
For Panels a d: Row: particle release location, Column: particle exit location.
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