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Therefore, extinction of M296I was favored by prior R mutagenesis, and a minimum mutagenic dose by FU was required for extinction.
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As important as the type of mutagen is the mutagenic dose and exposure time.
Both skin sites receiving the same mutagenic dose of UVR may explain this phenomenon.
This difference reflects the considerably higher toxicity of swimming pool water relative to drinking water, with the highest testable mutagenic dose of pool water being the lowest mutagenic dose of drinking water.
The Muta™ Mouse transgene mutation assay was used, and DNA adducts were quantified to confirm delivery of a mutagenic dose of BaP to the liver.
Density-inhibited cultures were exposed to cytotoxic and mutagenic doses.
This was done by deleting one copy of the Ink4a tumor suppressor gene and exposure to mutagenic doses of UV-light.
Prescribed daily doses were below minimum recommended daily dose (MRDD) in 26% of 43 dogs with sufficient information for calculation of minimum dose.
25 mg sumatriptan was the minimum effective dose [6].
The minimum adsorbent dose corresponding to the maximum removal is the optimum dose.
The minimum lethal dose for humans has not been established.
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