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The minimum measurable phase difference is limited by the standard deviation of the random variable for which Δ φ i is a realization [ 17].
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In practice, the minimum measurable axial velocity in tissue is limited by the phase decorrelation associated with trigger jitter and scanning the beam [ 25].
After applying a phase compensation algorithm where bulk motion was calculated and removed using a histogram-based method [ 23], the standard deviation of phase differences between successive sweeps over a mirror was measured to be 0.11 rad, corresponding to a minimum measurable axial velocity of 0.7 mm/s in tissue.
The minimum concentration change that can be measured is about 30 ppm, which is equivalent to a minimum measurable change of refractive index of 5 × 10−5.
From Eq. (3), it is obvious that the minimum measurable absorption (Amin), or sensitivity (ΔA), is determined by the accuracy of ΔI/I0 measurements.
Minimum measurable Reynolds number obtained with this technique is 5000 which is significantly lower than conventional vortex flowmeters.
The minimum measurable displacement is found to be 18 nm at 3.4 kHz with a signal-to-noise ratio of around 6 dB.
However, before the thermopower waves reached the ending position, the temperature at the ignition point decreased below the minimum measurable temperature of the optical pyrometer.
Maximum detection depth and the minimum measurable SPION concentration were determined experimentally.
Nevertheless, the small displacements can lead to a measurable phase shift of the interference spectrum.
This is a limitation referred to as phase wrapping [ 18] and sets the upper limit of measurable phase difference, without the need for complicated phase unwrapping algorithms.
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