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Exact(17)
LD50 is the minimum lethal dose for which we observe a 50% mortality of larvae.
The activity of each antimicrobial agent and its combination was assessed in a murine peritonitis model (n=15), using the minimum lethal dose (MLD) of Pa4 as inoculum.
The minimum lethal dose for humans has not been established.
As a comparison, in one test the minimum lethal dose of for a guinea pig was 40 67 mg, but only 1.7 mg was necessary when Daboia russelii venom was used.
The minimum lethal dose is the highest virus dilution that causes all embryos inoculated with that dilution to die.
The MDT recorded was the mean time (in hours) required for the minimum lethal dose to kill the embryos and the EID50 was calculated by the method of Reed and Muench.
Similar(43)
The neuronal loss and mortality in these studies proved to be dose-dependent, being absent with 500 minimum lethal doses and mortality being higher and earlier with 2000 minimum lethal doses (Bagetta et al., 1990).
Determination and quantification of methanol and ethanol concentration in alcoholic drinks and some local fermented food products showed that some amounts of methanol between the ranges of "not detectable" to 0.161% were found in most of the alcoholic drinks that were investigated, but were however below the minimum oral lethal dose 0.3 1 g/kg (20 to 60 g or 25 75 ml/person in a 60 kg adult).
Early studies estimated a minimum human lethal dose (LD100) of BoNT/A at 1 ng per kg body mass when administered via inter-peritoneal injection [9], but it has since been recognized that the route of toxin exposure is critical in determining its lethality.
Because all inoculated birds died, regardless of dose, the minimum infectious and lethal doses could not be calculated, but was less than 10 EID50, the smallest virus dose administered.
lethal dose with 50% lethality.
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