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Minimum incidence estimates per 1,000 children <17 years of age, based on the number of reported cases, decreased by 76.9%, from 26.0 per 1,000 children <17 years of age in the first season to 6.0 in the fifth season (Table 5); for the age groups <1, 1-4, 5-9, and 10-16 years, the incidences decreased by 79.9%, 80.6%, 73.9% and 47.4%, respectively.
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Automated blood culture, manual speciation, serotyping, and antimicrobial susceptibility testing were performed at MLW. Population data for minimum-incidence estimates in urban Blantyre were drawn from published estimates.
Systemic AL amyloidosis was the most common type with an estimated minimum incidence of 0·3/100 000 population.
The estimated minimum incidence of systemic amyloidosis in the English population in 2008, based on new referrals to the NAC, was 0·4/100 000 population.
According to the estimated minimum incidence, in 9 villages the disease was classified as highly endemic, and in 15 villages, the disease was considered of low endemicity.
The SEER program‐reported trend of −12.5% for 2010 2012 was detected by JoinPoint based on three annual incidence estimates, the minimum number of data points required to describe a trend 2. Our analysis by month estimated the trend to be steeper, −19.6% APC, and to start later, in May 2011.
We also estimated the minimum incidence in children aged 15 years and under.
We also estimated the minimum incidence rate for each of the 27 villages served by our hospital; a high incidence rate was defined as >1.5%.
We were also unable to estimate the minimum incidence of neonatal admissions due to lack of information on live births in the catchment area.
These data enabled us to estimate the minimum incidence of mild-to-severe acute Q fever to be 20 cases/1 million persons/y, which is similar to that observed in Provence-Alpes-Côte d'Azur (19 cases/1 million persons/y) but lower than that observed in Bouches du Rhône (40 cases/1 million persons/y in 2009).
Our disease estimates are of minimum incidence, as it is well described that routine surveillance supported by CSF culture alone may underestimate meningitis incidence [ 38].
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