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The results obtained show the potential of MBDoE for quick development and assessment of electrodialysis models, where highly predictive capability can be achieved with the minimum experimental time and waste of resources.
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An added benefit is that the method determines the minimum experimental testing time required on a machine; production management is then fully informed of the cost-to-production of establishing this important accuracy parameter.
For each experimental time point a minimum of five mice were evaluated.
The results presented reflect the absolute numbers of cells collected from a minimum of three animals at each experimental time point.
In the treated group, the withdrawal threshold, calculated using the "up and down" method, showed a decreasing trend of sensitivity threshold with a minimum at the end of the experimental time frame at 12 ± 5.1 gr (fig. 5).
The dotted line represents the theoretical minimum speed required for migrating interneurons to leave the MZ during the experimental time (14 h).
A minimum of 150 artifact-free deviant trials were recorded in each block, thus resulting in slightly over 60′ experimental time.
a, Experimental time course.
The total experimental time is 22 h.
For three and four cell cases, minimum stop band analytical transmissibilities lie below the minimum experimental measurements, although an experimental noise floor imposed a minimum transmissibility measurement of approximately 1.4×10−4.
Then, to optimize the experimental time and to reduce the protein quantity required for the NMR screening experiments, fragments were pulled into mixtures of 3 to 6 molecules with minimum spectral overlap.
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