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Sample size was chosen according to a minimum expected difference in pain control of different treatment regimes of 10%.
Based on prior literatures of applying MSE in healthy elderly subjects [44], [47], we estimated the total sample size to be at least 94 by assuming power of 80%, 1% significance level, minimum expected difference of 5 and estimated standard deviation of 5.
The minimum expected difference between the two means and the standard deviation were estimated to 10 mL/min/100 g each.
An effect size of 0.4 is equivalent to a decrease in the primary outcome of 1 point (the minimum expected difference between groups on a 0 10 scale) with an SD of 2.5.
To determine an appropriate sample size for this study, the standard recovery rate from the sample-limiting step of DNA extraction 90-955%) was used to determine the minimum expected difference of 10% or 0.10 [ 21].
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If the best model included a quadratic term we computed two values, the expected difference between the first month and the maximum or minimum (maximum or minimum – first month), and the expected difference between the maximum or minimum and the last month last monthh – maximum or minimum).
Spread: the expected difference between the teams' final scores.
The sample size calculation was based on a minimum expected frailty index difference of 0.04 between interventions based on NV-only and NV+AB versus usual care.
The minimum expected clinically important difference between breastfeeding rates at 6-8 wasks was 6.4% over two years, which in theory would have enabled Scotland to meet its government target of 50% of women breast feeding at 6 weeks by 2005.
may have leveled-out the expected differences.
The Pearson chi-square test was used to determine the differences between categorical variables unless the minimum expected cell frequency was less than five, in which case the Fisher's exact test was used instead.
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minimum expected count
minimum expected energy
minimum expected failure
minimum expected frequency
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minimum expected meeting
minimum expected pair
minimum expected length
minimum expected wavelength
minimum expected misclassification
minimum expected delay
minimum expected temperature
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minimum expected error
minimum expected utility
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CEO of Professional Science Editing for Scientists @ prosciediting.com