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Studies involving greater exercise doses tended to show larger effects, with the minimum dose to show a significant effect being 30 min at 50% ˙VO2max.
Several proton implants were performed in order to find the threshold dose (minimum dose to achieve maximum sheet resistivity) for the electrical isolation of n-type GaNxAs1−x layers.
Minimum dose to 70% of a volume.
The heterogeneity and mild renal failure of patients included in studies comparing different intensities of dialysis delivered in intermittent RRT prevent determination of the minimum dose to be delivered to patients with more severe disease.
Since D90 is the minimum dose to 90% of the tumor volume, it shows the most drastic difference since adjuvant RFA targets a relatively small fraction of tumor volume receiving the lowest dose.
Tumor and unablated tumor absorbed-dose metrics (average dose, D50, D70, D90, V100) following ablation were compared, where D70 is the minimum dose to 70% of tumor and V100 is the fractional tumor volume receiving more than 100 Gy.
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The D50, D70, D90, maximum and average tumor dose (D avg), and V100 were calculated for each tumor since these metrics were previously validated as prognostic indices for radioembolization [9], where D50 and D90 are the minimum doses to 50 and 90% of tumor volume and V100 is the percentage of tumor volume receiving more than 100 Gy.
It should be noted that AAA predicted up to 4% higher minimum doses to the PTVs in bone, where the gross tumor volume was located.
Accumulated minimum doses to the GTV (gross tumour volume) of <35 Gy, 35 45 Gy and >45 Gy, in six fractions were associated with 18-month local control of 33%, 55 % and 83, respectively.
These were used to establish the minimum dose required to ensure 100% transition from the pre-clinical to clinical disease status within a normal lifespan.
In addition, because bladder, rectum and bowel, and pelvis bone overlapped with the PTV, their maximum doses were correlated to the minimum dose delivered to the PTV.
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