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The concentration dependency of antimicrobial activity was assessed to determine the minimum dose that would give maximum benefit.
12, 16, 35 As soon as symptomatic control is achieved, the dosage is reduced to the minimum dose that suppresses the attacks.
The 600 mg dose of noni extract (equivalent to 20 g of dried noni fruit/ 8.712 mcg of scopoletin) was the minimum dose that effectively reduced the incidence of postoperative nausea in the early postoperative period [ 50].
65 The American Society for Radiation Oncology and American Urological Association panel view is that 64 65 Gy is the minimum dose that should be delivered post-prostatectomy, but decisions regarding dose should be made by the treating physician.
We assessed gene expression changes and epigenetic parameters relevant to carcinogenesis at furan doses lower than the minimum dose that has been shown to cause tumors, and closer to estimated exposure levels in humans.
The theory of threshold in toxicology is the minimum dose that its effect is likely to be similar to the background (i.e similar to dose zero) [ 15].
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Additional dose-response studies are needed to define the minimum antigen dose that will confer full protection against lethal viral infection.
We observed that depending on the cell or tissue of interest and the fluorescent marker used, a different optimal level of photobleaching may be required, which can be determined experimentally as the minimum photobleaching dose that will quench fluorescence of the reporter to a significant extend, without damaging the organism.
18 Most of the studies agree that 2 mg drospirenone is the minimum effective dose that can achieve a blood pressure decrease.
The proposed integrated procedure aims a) to identify the minimum effective dose that is statistically significant and that produces an effect that is at least of the relevant effect size, and b) if reliable, to estimate the corresponding dose for this effect size (BMD).
The high variability in lung IgA titres within the '+ mannan' group suggests that 1 μg H1N1 may correspond to the approximate minimum H1N1 dose that can be expected to induce detectable lung IgA in the majority of mice under the conditions tested.
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