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First, the EBL dose was varied until finding the minimum dose required to open sufficiently wide holes that subsequently enabled to completely etch the Ti layer underneath.
These were used to establish the minimum dose required to ensure 100% transition from the pre-clinical to clinical disease status within a normal lifespan.
Thus the minimum dose required for the termination of these transgenic plants is about 1000 mg/L, which is within the regular dose range used for normal rice weed control.
To determine the minimum dose required for terminating the transgenic rice, the transgenic plans of the four events, R450-2, R450-6, R450-7 and R450-7, were then further tested with spray of bentazon at 500, 1000 and 2000 mg/L, respectively.
Physical activity recommendations usually reflect the minimum dose required for general health or the point at which people accumulate substantial health benefit [1], [3] [6], [8] Clearly, because recommendations are seen as the lower limit of acceptable physical activity, it is imperative for individuals and healthcare practitioners that such judgments are consistent and unambiguous.
The minimum dose of 1, 9 PA necessary to downregulate HIF-1α was between 1.25 and 2.5 µM, which was slightly higher than the minimum dose required to effectively reduce c-Jun phosphorylation through inhibition of JNK (between 0.6 and 1.25 µM; Figure 1B), which further suggests that the newly discovered downregulatory effect of 1, 9 PA on HIF-1α is independent of its known inhibitory effect on JNK.
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Initially, two strategies were evaluated; xylanase supplementation of the minimum cellulase dose required for effective cellulose hydrolysis, and replacement of a portion of the minimum cellulase dose with xylanase while keeping the total protein loading constant.
In terms of minimum radiation dose required to effect treatment, the range is reported as being as large as <50 495 Gy [20], and methodologies vary.
Collectively, these data reveal that 1×1010 GC/mouse is the minimum effective dose required for complete correction; furthermore, partial correction can be attained with as little as 3×109 GC/mouse.
Minimum cell dose required for the CD34+ enriched progenitor cell graft was 2 × 10 cells/kglls/kg.
It is licensed in the dose range of 100 900 mg; however, patients with renal impairment are recommended to take the minimum effective dose required to achieve urate control.
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