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It has been reported that a minimum daily dose of 109 cfu/day of the strain L. johnsonii LA1 is required to modulate non-specific immune response, however the same effect was not observed at a lower cfu/day of 106 [44].
To continue in the study, subjects had to maintain a minimum daily dose of 50 mg.
The effect was dose-dependent (Fig 1B), and the minimum daily dose for complete prevention was 5 mg/kg/day.
The dosage of dapsone in nearly all sulfone-sensitive disorders must be individually titrated to determine the minimum daily dose that effectively controls symptoms.
In meta-analyses, a minimum daily dose of daily 700 IU vitamin D3 was considered necessary to prevent falls and osteoporotic fractures [ 34- 36].
The FDA and the AHA recommend that adults stick to the minimum daily dose, which is only 75 to 81 milligrams.
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The minimum daily opioid dose for study inclusion was 30 mg of oral morphine or equianalgesic amount(s) of one or more other opioid therapies.
The minimum recommended daily dose was used as an estimate of the dose needed to achieve 50% of the maximum effect.
Each drug therapy preferably started with the minimum effective daily dose regimen, except for when a prior, ineffective regimen was already in the clinical records of the patient.
A minimum probiotic daily dose of 10-10 cfu has been recommended in processed foods in order to exert their beneficial effects [ 35, 39].
In the next step we assessed the association between minimum mean daily dose of insulin necessary to normalize glucose concentration at the beginning of therapy and HOMA-IR.
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