The minimum cluster size for significance at p = .05 was 615 contiguous voxels.
Since most runners have only a few routes available, a threshold of minimum cluster size S=3 was considered reasonable.
We use a minimum cluster size Cmin=5, a clustering threshold Z θ =0.3, and a distance threshold d θ =150 m.
A threshold p<0.001 corrected for multiple comparisons and a minimum cluster size of 16 voxels provided the significance criteria.
A p<.005 voxelwise threshold and a.225 ml minimum cluster size was the criterion for significance.
Functional imaging results are reported as t-scores with a threshold of p<0.02 (uncorrected) and a minimum cluster size of 15 contiguous voxels.
For all group analyses, we applied a voxel-wise threshold of p<0.05 (family wise error corrected) and a minimum cluster size of 10 coherent voxels.
SPM-T maps of GM and WM damage and hypometabolism were thresholded using an FDR-corrected p-value of <0.001, with a minimum cluster size of 200 voxels.
For the basal ganglia/midbrain volume, a voxelwise threshold of p<.008 and a minimum cluster size of.225 ml yielded a.05 familywise alpha.
All results were threshold at uncorrected p<.005 (seed) and p<.05 (extension), and a minimum cluster size 150 voxels×(0.08×0.08×0.08) mm/voxel = 0.0768 mm3.
For the cortical volume, a voxelwise threshold of p<.004 and a minimum cluster size of.338 ml yielded a.05 familywise alpha.
