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We did a sweep for the ' s' (size) and ' d' (minimum cluster density) parameters in ClusterOne [ 25].
DPClus was used to cluster both experiments with the following parameters: minimum cluster density of 0.75; CP threshold of 0.75; minimum cluster size of 3 for experiment #1 and 5 for experiment #2; allowing overlapping clusters to form [ 29].
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An FDR-corrected p-value of <0.01 with a minimum cluster size of 200 voxels was used for the comparison between GM density abnormalities and hypometabolism.
We used the nonoverlapping mode with the following DPClus settings: Cluster property cp nk was set to 0.5, density value d k was set to 0.6, and minimum cluster size was set to 2. We also performed a classification of VOCs based on their chemical structure similarity.
Minimum cluster size = 25 voxels.
QT clustering algorithm groups genes into high quality clusters based on two parameters: "minimum cluster size" and "minimum correlation".
Moreover, a minimum cluster size of 200 mm was chosen.
The minimum cluster size was set to 10 and minimum correlation to 0.75 (Pearson correlation).
The minimum cluster size was set to 30 and minimum correlation to 0.80.
A minimum cluster size of 5 genes was applied.
Various values of minimum cluster size were tested.
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