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Where control in the vertical plane was concerned, distal placement of the mini screw with the 6-mm power arm height had minimum adverse effect on anterior dentition.
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Likewise, these could be used in chronic treatments with minimum adverse effects.
In conclusion, developed NLCs-based gel formulation loaded with MTX opens new avenues for developing novel therapeutic modality for RA patients with the acceptably minimum adverse effects.
Finding the appropriate dosage that generates a sufficient enhancement effect with minimum adverse effects would be the prerequisite to translate animal study into clinical use.
Further studies will provoke Ginkgetin as a promising candidate for anti-medulloblastoma drug development, thus providing novel therapeutic strategies for MB with minimum adverse effects.
Recently, high cure rates and minimum adverse effects were reported among patients with uncomplicated falciparum malaria treated with SMP [ 10].
Guidelines need to be evidence-based to ensure the best outcome for the patient with minimum adverse effects, as well as being easy to follow, clinically relevant, comprehensive, and flexible for busy clinicians [ 5].
Lundstrom and Furst (2006) have argued that guidelines need to be evidence-based to ensure the best outcomes for patients with minimum adverse effects, as well as being easy to follow, clinically relevant, comprehensive, and flexible [ 2].
With the implementations of in silico and "omics" technologies and 2D and 3D quantum and docking studies now therapeutic entities are being developed targeting the enzymatic and receptor signaling pathways and drug molecules are structurally modified to achieve maximal therapeutic outcomes with minimum adverse effects [ 7].
Transcranial Direct Current Stimulation (tDCS) is a promising method involving low-cost equipment that is easy to administer and offers good patient tolerance with minimum adverse effects [ 15]. tDCS has been used in combination with physical therapy to potentiate neuroplastic changes [ 13].
Minimal adverse effects.
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