Sentence examples for minimizing uptake from inspiring English sources

The imaging quality of FDG-PET in this preclinical study was optimized by minimizing uptake of FDG in other organs by anesthesia, fasting, and warming of the animals [45].

MM-302 is a HER2-targeted liposomal doxorubicin designed for selective uptake into HER2-overexpressing tumor cells, while minimizing uptake into non-target cells and tissues such as cardiomyocytes.

The mice were not fasted prior to the [18F]FDG experiment in order to minimize uptake to the tumor and allow for easier visualization of vasculature.

To reduce the attachment of serum protein and minimize uptake of RES for systemic injection, extensive PEGylation was applied to generate LPR.

Mice were maintained on a low-iodine diet and T4 supplementation (5 mg/L) in their drinking water throughout the duration of the experimentation to maximize radioisotope uptake in the tumor and minimize uptake by the thyroid [ 8- 10].

To minimize uptake of the dye into organelles, 200 μmol L−1 of the anion transport inhibitor sulphinpyrazone was dissolved in dimethyl sulphoxide (DMSO) and included in the medium during loading and de-esterification.

The hydrophilic polymers can be used to coat nanoparticles to extend their circulation time by reducing protein adsorption through the hydrophilicity or steric properties, which are thought to minimize uptake by RES cells [ 24].

PEGylation on small-sized liposomes is known to minimize uptake into phagocytic cells such as macrophages, which results in extended circulation times, but may be counterindicated for the treatment of inflammatory disorders where macrophages are key producers of proinflammatory cytokines.

In the FDA approved protocol, 250 mg/m unlabeled rituximab is given to the patient 48 72 hrs prior to performing the In-Zevalin scan (5 mgin1.6 mg) in order to minimize uptake of In-Zevalin in normal tissues and blood mononuclear cells [ 63].

In both cases the flux distributions were ascertained by limiting the specific growth rate and the fructose uptake (where applicable) to the experimentally measured values and minimizing the uptake of CAAs.

These studies indicated that chemotherapy administered 24 hours before the injection of 111In-DOTA-DAB4 111In-DOTA-DAB4 111In-DOTA-DAB4maximized its uptumorby critical organs (Al-Ejeh et al., accompanying manuptaket).