Sentence examples for minimizing trial from inspiring English sources

Due to the large numbers of ineffective, and frequently toxic, agents studied in phase II, ethics dictate that many phase II clinical trials employ a two-stage method, which may be designed with the goals of minimizing trial size when agents are truly ineffective [ 21, 22].

In this study, a computer-aided-design (CAD) system to support roll pass and roll profile design of bar rolling, where simple shapes like round and square bars are produced, was developed in order to minimize trial and errors in industry.

The investigators used a standard method to set up and monitor responses using the TOF-Watch® SX, in order to minimize trial center variability.

In order to minimize trial size, we chose change in tumor burden at 8 weeks as assessed by response evaluation criteria in solid tumors (RECIST) measurements as the primary endpoint since recent analyses by our group suggested that this metric correlates well with the traditional PFS endpoint.

In this study trials were only considered when the confidence rating was greater than or equal to 2, thus minimizing the trials that involved significant guessing.

In a parallel-group minimized controlled trial, patients were recruited before hospital discharge or in the intensive care follow-up clinic and enrolled 8 16 weeks after discharge.

This was an exploratory parallel-group minimized controlled trial that compared the effect of an 8-week exercise intervention, delivered after hospital discharge, with current usual care of follow-up by appropriate medical and surgical specialties but no formal rehabilitation programme.

To increase the number of WIN and LOSS trials within 245 trials for minimizing the scanning time, some trial sequences consisted of four or five continuous win/lose outcomes, and the fourth and fifth trials in these sequences were included in analysis.

Subjective investigator assessments of treatment effects were therefore avoided in this trial, minimizing bias.

The ability to pinpoint the source and effects of torsional, axial and lateral oscillations enables users to qualify design changes to the drill-string configuration and optimize parameters, prior to drilling the well, thus minimizing the traditional "trial" and "error" approach and operator risk.

A design of experiments is used to compute the mathematical model and to minimize the trials number.