Sentence examples for minimizing toxicity to from inspiring English sources

One of the most exciting areas was the development of molecular target-specific therapeutics that have the potential to maximize therapeutic benefit while minimizing toxicity to normal cells.

With the hope of selectively targeting other critical components of cancer growth and survival while minimizing toxicity to the host, numerous strategies have been developed to inhibit receptor tyrosine kinases for various growth factors commonly expressed by cancer cells.

The design of various types of macromolecular architectures with control of structural parameters such as hydrophobicity/hydrophilicity balance, molecular weight, and ionic groups will be emphasized in order to achieve strong antimicrobial activities while minimizing toxicity to mammalian cells.

With appropriate engineering, these GNP-based platforms have the capacity for controlled delivery of therapeutic doses, while minimizing toxicity to the healthy organs and tissues.

This NSC-mediated therapeutic approach would overcome current limitations of standard therapies, while minimizing toxicity to normal tissues [19], [20].

New treatment modalities, including immunotherapy, gene therapy and drug delivery across the blood-brain barrier (BBB), have yet to achieve significant clinical success due to shortcomings in effectively targeting these invasive tumor cells, while minimizing toxicity to normal tissue [2].

Targeting another insect-specific residue in addition to Cys289 or its equivalent might minimize toxicity to bees or silkworms.

We used the rat transplacental model described by Gómez-Meda et al., [ 16], which is based on exposing pregnant rats to the test agent from day 16 to 21 of gestation (the final stage of the organogenesis) in order to minimize toxicity to the developing fetuses.

Further clinical data with long follow-up period are needed to ascertain the dose fractionations schedule that optimizes tumor control while minimizing toxicity and to better understand the optimal normal tissue dose volume constraints.

These therapies have the potential to selectively target tumors, to minimize toxicity, and to overcome the resistance often observed with conventional therapies [ 15].

Treatment schemas emphasize the importance of minimizing toxicity and treatment duration, while attempting to improve therapeutic efficacy.