Investigators believed that this finding provided one potential mechanism for the loss of CAR-T cells observed in other trials and concluded that Cy/Flu could minimize the substantial cellular immune response against CAR.
To prevent fluid overload and minimize the substantial burden it places upon patients and health care systems, approaches to fluid management should be reviewed and standardized.
Perhaps, the essential functions of these gene products correspond to the biased amino acid composition that might minimize the substantial biosynthesis energy costs indicating the high biological significance of these genes.
As the US population ages and the incidence of fluid overload increases, better approaches to fluid and coagulation management, with improved efficacy, safety, and cost-effectiveness, are needed to prevent fluid overload and minimize the substantial burden it places on patients and health care systems.
A seven day period was chosen to decrease the chance of participants recalling their response from the previous administration while also minimizing the chance of substantial life changes between assessments [ 21].
Those who did not return the FFQ were more likely to have annual incomes less than $20,000 and less than a high school education [ 24]; however, the ~900 people of lower socioeconomic status who did return the FFQ were similar in terms of race, age, sex or history of cardiovascular disease from those who did not return the FFQ, minimizing the likelihood of substantial bias.
Yet as recently as June of last year he could be found minimizing the possibility of a substantial economic downturn.
Numerical multi-physics methods, on the other hand, enable minimizing the simplified assumptions but require substantial computational expertise, which is not always available.
The rapid pace of technological evolution places a substantial amount of pressure on minimizing the time-to-market for integrated circuit designers.
Significant currents can be induced without having to apply substantial voltages across the skull, minimizing the activation of pain fibers and pain sensation.
